Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | SI | P14410 | 4/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593111 | 0.92 | MAPT (0.57) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL5592998 | 0.88 | MAPT (0.52) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL5593139 | 0.80 | KDM4E (0.53) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL17051667 | 0.80 | MEN1 (0.62) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL5593047 | 0.80 | ALDH1A1 (0.57) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL17051672 | 0.80 | MEN1 (0.62) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL22912193 | 0.79 | SDHB (0.60) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL17051500 | 0.79 | MEN1 (0.60) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL17051660 | 0.79 | MEN1 (0.60) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL13133556 | 0.79 | MAPT (0.58) | MAPTKDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007074238-A2 | NOVEL N-ALK-(E)-YLIDENE-N'-PYRIMIDIN-2-YL HYDRAZINE DERIVATIVES AND USE THEREOF AS CYTOPROTECTIVE DRUGS | TROPHOS (FR) | 2007-07-05 | — | — | WO | disclosed |