Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 16/20 | 0.51 |
| ▸ | MTOR | P42345 | 13/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593318 | 0.85 | PIK3CA (0.53) | PIK3CAMTORPIK3CGPIK3CDHTT | |
| SCHEMBL5593024 | 0.83 | PIK3CA (0.56) | PIK3CAMTORPIK3CGPIK3CDHTT | |
| SCHEMBL5603844 | 0.82 | PIK3CA (0.52) | PIK3CAMTORPIK3CGPIK3CDHTT | |
| SCHEMBL5593037 | 0.80 | PIK3CA (0.66) | PIK3CAMTORPIK3CGPIK3CDHTT | |
| SCHEMBL5592979 | 0.79 | PIK3CA (0.66) | PIK3CAMTORPIK3CGPIK3CDHTT | |
| SCHEMBL5603608 | 0.79 | MTOR (0.60) | PIK3CAMTORPIK3CGPIK3CDHTT | |
| SCHEMBL5592988 | 0.78 | PIK3CA (0.61) | PIK3CAMTORPIK3CGPIK3CDHTT | |
| SCHEMBL5593072 | 0.74 | PIK3CA (0.62) | PIK3CAMTORPIK3CGPIK3CDHTT | |
| SCHEMBL5593293 | 0.74 | PIK3CA (0.58) | PIK3CAMTORPIK3CGPIK3CDHTT | |
| SCHEMBL4934392 | 0.72 | PIK3CA (0.66) | PIK3CAMTORPIK3CGPIK3CDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007066099-A1 | PYRIMIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2007-06-14 | — | — | WO | claimed |