Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 6/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593258 | 0.96 | ALOX15 (0.34) | MAPK1ALOX15TSHREGLN2PDE2A | |
| SCHEMBL5593468 | 0.95 | CDK2 (0.34) | MAPK1ALOX15TSHREGLN2PDE2A | |
| SCHEMBL5593147 | 0.90 | PDE2A (0.36) | MAPK1EGLN2PDE2ASMN1; SMN2HPGD | |
| SCHEMBL5593250 | 0.87 | MAPK1 (0.40) | MAPK1ALOX15TSHREGLN2SMN1; SMN2 | |
| SCHEMBL5593351 | 0.86 | PDE2A (0.37) | PDE2ASMN1; SMN2HPGD | |
| SCHEMBL5593153 | 0.85 | TSHR (0.36) | MAPK1ALOX15TSHREGLN2PDE2A | |
| SCHEMBL5593435 | 0.85 | PDE2A (0.37) | PDE2AHPGD | |
| SCHEMBL5593138 | 0.83 | MAPK1 (0.39) | MAPK1ALOX15TSHRPDE2APOLB | |
| SCHEMBL5593478 | 0.83 | EGLN2 (0.41) | MAPK1ALOX15TSHREGLN2PDE2A | |
| SCHEMBL5593106 | 0.82 | TSHR (0.38) | MAPK1ALOX15TSHRPDE2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007099092-A1 | SUBSTITUTED 6-PHENYL-7-AMINO[1,2,4]-TRIAZOLO[1,5-a]PYRIMIDINES AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI | BASF SE (DE) | 2007-09-07 | — | — | WO | claimed |