Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 5/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | GRM8 | O00222 | 1/20 | 0.33 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.33 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593351 | 0.96 | PDE2A (0.37) | PDE2AIRAK4CYP1A2HPGDSMN1; SMN2 | |
| SCHEMBL5593435 | 0.95 | PDE2A (0.37) | PDE2ACYP1A2HPGDALDH1A1HTT | |
| SCHEMBL5593259 | 0.90 | MAPK1 (0.35) | PDE2AHPGDSMN1; SMN2EGLN2MAPK1 | |
| SCHEMBL5593060 | 0.90 | CYP1A2 (0.39) | PDE2AIRAK4CYP1A2HPGDSMN1; SMN2 | |
| SCHEMBL5593148 | 0.89 | PDE2A (0.36) | PDE2AIRAK4CYP1A2HPGDSMN1; SMN2 | |
| SCHEMBL5593402 | 0.86 | EGLN2 (0.39) | PDE2AIRAK4CYP1A2HPGDEGLN2 | |
| SCHEMBL5593523 | 0.86 | PDE2A (0.39) | PDE2ACYP1A2HPGDSMN1; SMN2LMNA | |
| SCHEMBL5593258 | 0.86 | ALOX15 (0.34) | PDE2AEGLN2MAPK1 | |
| SCHEMBL5593123 | 0.85 | PDE2A (0.37) | PDE2ACYP1A2 | |
| SCHEMBL5593468 | 0.85 | CDK2 (0.34) | PDE2AEGLN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007099092-A1 | SUBSTITUTED 6-PHENYL-7-AMINO[1,2,4]-TRIAZOLO[1,5-a]PYRIMIDINES AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI | BASF SE (DE) | 2007-09-07 | — | — | WO | claimed |
| WO-2007099092-A1 | SUBSTITUTED 6-PHENYL-7-AMINO[1,2,4]-TRIAZOLO[1,5-a]PYRIMIDINES AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI | BASF SE (DE) | 2007-09-07 | — | — | WO | disclosed |