Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 17/20 | 0.51 |
| ▸ | RAF1 | P04049 | 1/20 | 0.51 |
| ▸ | BRAF | P15056 | 1/20 | 0.51 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593449 | 0.86 | CSF1R (0.57) | MAPK14RAF1BRAFCSF1R | |
| SCHEMBL5592959 | 0.84 | MAPK14 (0.53) | MAPK14RAF1BRAFCYP3A4CYP2C9 | |
| SCHEMBL5593303 | 0.76 | RAF1 (0.59) | MAPK14RAF1BRAFPLAU | |
| SCHEMBL4827472 | 0.75 | RAF1 (0.64) | MAPK14RAF1BRAFCSF1RCYP3A4 | |
| SCHEMBL4829487 | 0.72 | RAF1 (0.60) | MAPK14RAF1BRAFPLAU | |
| SCHEMBL12764328 | 0.71 | BRAF (0.59) | MAPK14RAF1BRAFPLAU | |
| SCHEMBL4552283 | 0.71 | RAF1 (0.56) | MAPK14RAF1BRAFCSF1R | |
| SCHEMBL4407767 | 0.71 | CNR1 (0.43) | MAPK14RAF1BRAFCSF1R | |
| SCHEMBL6477438 | 0.70 | MAPK14 (0.67) | MAPK14RAF1BRAFCSF1R | |
| SCHEMBL4410023 | 0.70 | RAF1 (0.55) | MAPK14RAF1BRAFCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |