Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 5/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | BRAF | P15056 | 14/20 | 0.51 |
| ▸ | RAF1 | P04049 | 14/20 | 0.51 |
| ▸ | LYN | P07948 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593307 | 0.86 | MAPK14 (0.51) | CSF1RMAPK14BRAFRAF1 | |
| SCHEMBL5593403 | 0.81 | TEK (0.44) | CSF1RBRAF | |
| SCHEMBL4829508 | 0.77 | CSF1R (0.68) | CSF1RMAPK14BRAFRAF1 | |
| SCHEMBL5593445 | 0.77 | RAF1 (0.58) | CSF1RMAPK14BRAFRAF1 | |
| SCHEMBL25534818 | 0.76 | CSF1R (0.71) | CSF1RMAPK14BRAFRAF1LYN | |
| SCHEMBL5592959 | 0.76 | MAPK14 (0.53) | MAPK14BRAFRAF1 | |
| SCHEMBL25238622 | 0.73 | CSF1R (1.00) | CSF1RMAPK14BRAFRAF1LYN | |
| SCHEMBL1420016 | 0.72 | RAF1 (0.65) | CSF1RBRAFRAF1 | |
| SCHEMBL6978589 | 0.72 | CSF1R (0.72) | CSF1RMAPK14BRAFRAF1LYN | |
| SCHEMBL4552241 | 0.72 | RAF1 (0.63) | CSF1RBRAFRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |