Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 12/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4407765 | 0.76 | RAF1 (0.45) | CNR1NPC1RAB9AUSP2ALDH1A1 | |
| SCHEMBL5593307 | 0.71 | MAPK14 (0.51) | CSF1RMAPK14RAF1BRAF | |
| SCHEMBL5593311 | 0.71 | RAF1 (0.46) | CSF1RRAF1BRAF | |
| SCHEMBL5593449 | 0.70 | CSF1R (0.57) | CSF1RMAPK14RAF1BRAF | |
| SCHEMBL5592959 | 0.67 | MAPK14 (0.53) | SMN1; SMN2MAPK14RAF1BRAFTP53 | |
| SCHEMBL4541481 | 0.67 | RAB9A (0.47) | NPC1RAB9ACSF1RMAPK14RAF1 | |
| SCHEMBL4410942 | 0.66 | BRAF (0.45) | CSF1RRAF1BRAF | |
| SCHEMBL4412596 | 0.66 | ACKR3 (0.43) | NPC1RAB9ACSF1RMAPK14RAF1 | |
| SCHEMBL5593352 | 0.66 | RAF1 (0.41) | NPC1RAB9AUSP2ALDH1A1SMN1; SMN2 | |
| SCHEMBL4412693 | 0.66 | RAF1 (0.49) | CSF1RRAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035005-A2 | THERAPY USING CYTOKINE INHIBITORS | Kemia, INC. (US) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007146712-A2 | THERAPY USING CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-12-21 | — | — | WO | disclosed |