Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593421 | 0.80 | L3MBTL1 (0.43) | GAASMN1; SMN2L3MBTL1MEN1KMT2A | |
| SCHEMBL5593368 | 0.77 | GAA (0.43) | MAPTLRRK2GAABRAFSMN1; SMN2 | |
| SCHEMBL4419761 | 0.73 | CYP1A2 (0.49) | MAPTGAASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL4410927 | 0.72 | CYP1A2 (0.51) | MAPTGAASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL4407658 | 0.71 | NPC1 (0.42) | LRRK2GAABRAFL3MBTL1CYP1A2 | |
| SCHEMBL14473258 | 0.70 | CYP1A2 (0.48) | MAPTGAASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL4016214 | 0.70 | TEK (0.51) | GAACYP3A4MEN1KMT2AABL1 | |
| SCHEMBL4013698 | 0.69 | ABL1 (0.53) | BRAFCYP3A4MEN1KMT2AABL1 | |
| SCHEMBL4417888 | 0.68 | CYP1A2 (0.65) | MAPTSMN1; SMN2HTTL3MBTL1CYP1A2 | |
| SCHEMBL4417707 | 0.68 | CYP3A4 (0.43) | MAPTGAABRAFSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |