Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5599163 | 0.86 | REN (0.64) | RENCYP3A4 | |
| SCHEMBL2846562 | 0.86 | REN (0.64) | RENCYP3A4 | |
| SCHEMBL3561103 | 0.84 | REN (0.62) | RENCYP3A4 | |
| SCHEMBL3561106 | 0.84 | REN (0.62) | RENCYP3A4 | |
| SCHEMBL8161123 | 0.84 | REN (0.62) | RENCYP3A4 | |
| SCHEMBL8140784 | 0.84 | REN (0.62) | RENCYP3A4 | |
| SCHEMBL4970928 | 0.77 | REN (0.46) | REN | |
| SCHEMBL2847131 | 0.76 | REN (0.65) | RENCYP3A4 | |
| SCHEMBL4294601 | 0.76 | REN (0.65) | RENCYP3A4 | |
| SCHEMBL3110107 | 0.76 | REN (0.64) | RENCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007117560-A2 | PIPERIDINE AND MORPHOLINE RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-10-18 | — | — | WO | disclosed |