Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 7/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA4 | P22748 | 3/20 | 0.46 |
| ▸ | CA6 | P23280 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11794375 | 0.98 | PTGS1 (0.51) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL29045688 | 0.84 | PTGS1 (0.50) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL4383362 | 0.83 | CYP26A1 (0.49) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL11788709 | 0.83 | PTGS1 (0.49) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL29169532 | 0.81 | NPC1 (0.57) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL7623394 | 0.81 | NPC1 (0.57) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL28547422 | 0.81 | PTGS2 (0.53) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL11790802 | 0.80 | NPC1 (0.56) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL29169546 | 0.80 | PTGS2 (0.57) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL9790769 | 0.80 | PTGS2 (0.57) | PTGS1PTGS2OPRK1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007072089-A1 | MGLUR5 ANTAGONISTIC CARBAMOYL-OXIME DERIVATIVES | RICHTER GEDEON VEGYÉSZETU GYÁR RT. (HU) | 2007-06-28 | — | — | WO | disclosed |