Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKB | Q96GD4 | 7/20 | 0.65 |
| ▸ | AURKA | O14965 | 6/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593700 | 1.00 | AURKB (0.65) | AURKBAURKAMAPTALDH1A1LMNA | |
| SCHEMBL5593985 | 0.93 | AURKB (0.66) | AURKBAURKAMAPTALDH1A1POLB | |
| SCHEMBL5594049 | 0.93 | AURKB (0.57) | AURKBAURKAMAPTALDH1A1LMNA | |
| SCHEMBL5594047 | 0.93 | AURKB (0.57) | AURKBAURKAMAPTALDH1A1LMNA | |
| SCHEMBL5594028 | 0.86 | AURKB (0.69) | AURKBAURKAMAPTALDH1A1POLB | |
| SCHEMBL5594031 | 0.86 | AURKB (0.69) | AURKBAURKAMAPTALDH1A1POLB | |
| SCHEMBL5594245 | 0.83 | AURKB (0.70) | AURKBAURKA | |
| SCHEMBL5593672 | 0.79 | AURKB (0.69) | AURKBAURKA | |
| SCHEMBL5594008 | 0.79 | AURKB (0.60) | AURKBAURKA | |
| SCHEMBL5594004 | 0.79 | AURKB (0.60) | AURKBAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058626-A1 | INDAZOLE COMPOUNDS | S*BIO PTE LTD (SG) | 2007-05-24 | — | — | WO | claimed |