Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKB | Q96GD4 | 9/20 | 0.66 |
| ▸ | AURKA | O14965 | 9/20 | 0.66 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593700 | 0.93 | AURKB (0.65) | AURKBAURKAHRH4MAPTALDH1A1 | |
| SCHEMBL5593704 | 0.93 | AURKB (0.65) | AURKBAURKAHRH4MAPTALDH1A1 | |
| SCHEMBL5594049 | 0.91 | AURKB (0.57) | AURKBAURKAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL5594047 | 0.91 | AURKB (0.57) | AURKBAURKAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL5593672 | 0.86 | AURKB (0.69) | AURKBAURKA | |
| SCHEMBL5593800 | 0.84 | AURKB (0.70) | AURKBAURKAALDH1A1 | |
| SCHEMBL5593859 | 0.80 | AURKB (0.62) | AURKBAURKAWDR5 | |
| SCHEMBL5603972 | 0.80 | AURKB (0.62) | AURKBAURKAWDR5 | |
| SCHEMBL5594028 | 0.79 | AURKB (0.69) | AURKBAURKAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL5594031 | 0.79 | AURKB (0.69) | AURKBAURKAMAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058626-A1 | INDAZOLE COMPOUNDS | S*BIO PTE LTD (SG) | 2007-05-24 | — | — | WO | claimed |