Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKB | Q96GD4 | 7/20 | 0.57 |
| ▸ | AURKA | O14965 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5594049 | 1.00 | AURKB (0.57) | AURKBAURKAALDH1A1L3MBTL1LMNA | |
| SCHEMBL5593700 | 0.93 | AURKB (0.65) | AURKBAURKAALDH1A1L3MBTL1LMNA | |
| SCHEMBL5593704 | 0.93 | AURKB (0.65) | AURKBAURKAALDH1A1L3MBTL1LMNA | |
| SCHEMBL5593985 | 0.91 | AURKB (0.66) | AURKBAURKAALDH1A1L3MBTL1POLB | |
| SCHEMBL5594004 | 0.87 | AURKB (0.60) | AURKBAURKA | |
| SCHEMBL5594008 | 0.87 | AURKB (0.60) | AURKBAURKA | |
| SCHEMBL14538848 | 0.84 | AURKA (0.59) | AURKBAURKAALDH1A1L3MBTL1LMNA | |
| SCHEMBL5616552 | 0.84 | AURKB (0.61) | AURKBAURKATDP1 | |
| SCHEMBL5593744 | 0.82 | AURKB (0.62) | AURKBAURKA | |
| SCHEMBL5593748 | 0.82 | AURKB (0.62) | AURKBAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058626-A1 | INDAZOLE COMPOUNDS | S*BIO PTE LTD (SG) | 2007-05-24 | — | — | WO | claimed |