Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13693766 | 1.00 | KDM1A (0.36) | KDM1AHRH3HRH2HRH1LTA4H | |
| SCHEMBL3933502 | 0.88 | L3MBTL3 (0.38) | L3MBTL3ADH1CADH1A | |
| SCHEMBL27698003 | 0.82 | KDM1A (0.37) | KDM1AHRH3HRH2HRH1LTA4H | |
| SCHEMBL3939592 | 0.81 | ADH1C (0.32) | ADH1CADH1A | |
| SCHEMBL29957271 | 0.81 | KDM1A (0.40) | KDM1AHRH3HRH2HRH1 | |
| SCHEMBL13162619 | 0.79 | SLC18A3 (0.38) | KDM1AHRH3HRH2HRH1LTA4H | |
| SCHEMBL684126 | 0.75 | HRH3 (0.41) | KDM1AHRH3HRH2HRH1LTA4H | |
| SCHEMBL8434577 | 0.75 | HRH3 (0.41) | KDM1AHRH3HRH2HRH1LTA4H | |
| SCHEMBL734698 | 0.75 | HRH3 (0.41) | KDM1AHRH3HRH2HRH1LTA4H | |
| SCHEMBL4371589 | 0.74 | KDM1A (0.43) | KDM1AHRH3HRH2HRH1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| WO-2007070816-A2 | THIOPHENE DERIVATIVES AS FACTOR XIA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-06-21 | — | — | WO | disclosed |