Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | TYR | P14679 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 2/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5673590 | 0.82 | KDM4E (0.62) | KDM4EKMT2ASMN1; SMN2CA12CA1 | |
| SCHEMBL5673587 | 0.82 | KDM4E (0.62) | KDM4EKMT2ASMN1; SMN2CA12CA1 | |
| SCHEMBL21620882 | 0.81 | APP (0.69) | KDM4EKMT2ASMN1; SMN2CA12CA1 | |
| SCHEMBL28989627 | 0.81 | APP (0.57) | CA12CA1CA7CA9CA14 | |
| SCHEMBL14619003 | 0.81 | KDM4E (0.61) | KDM4EKMT2ASMN1; SMN2CA12CA1 | |
| SCHEMBL5593815 | 0.81 | KDM4E (0.61) | KDM4EKMT2ASMN1; SMN2CA12CA1 | |
| SCHEMBL69618 | 0.79 | TTR (0.66) | KDM4EKMT2ASMN1; SMN2CA12CA1 | |
| SCHEMBL5593851 | 0.78 | ALDH1A1 (0.45) | KDM4EKMT2ASMN1; SMN2CA12CA1 | |
| SCHEMBL1481293 | 0.75 | TTR (0.61) | KDM4EKMT2ASMN1; SMN2CA12CA1 | |
| SCHEMBL18405874 | 0.75 | APP (0.61) | KDM4EKMT2ASMN1; SMN2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007022263-A1 | FLUOROGENIC PROBES FOR MEDIUM CHAIN ACYL-COA DEHYDROGENASE ( MCAD ) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2007-02-22 | — | — | WO | disclosed |