Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GUSB | P08236 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28989931 | 0.82 | APP (0.45) | ALDH1A1KDM4EMAPTHPGDKMT2A | |
| SCHEMBL29030083 | 0.81 | GUSB (0.44) | ALDH1A1KDM4EMAPTHPGDKMT2A | |
| SCHEMBL7741457 | 0.81 | KDM4E (0.46) | ALDH1A1KDM4EMAPTHPGDKMT2A | |
| SCHEMBL7741456 | 0.81 | KDM4E (0.46) | ALDH1A1KDM4EMAPTHPGDKMT2A | |
| SCHEMBL17183786 | 0.80 | GUSB (0.50) | ALDH1A1KDM4EMAPTHPGDKMT2A | |
| SCHEMBL5292811 | 0.80 | HDAC8 (0.64) | ALDH1A1KDM4EMAPTHPGDKMT2A | |
| SCHEMBL5593853 | 0.78 | KDM4E (0.57) | ALDH1A1KDM4EMAPTHPGDKMT2A | |
| SCHEMBL31174396 | 0.78 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTHPGDKMT2A | |
| SCHEMBL23606857 | 0.77 | KMT2A (0.49) | ALDH1A1KDM4EMAPTHPGDKMT2A | |
| SCHEMBL5593811 | 0.76 | CCNC (0.50) | ALDH1A1KDM4EMAPTHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007022263-A1 | FLUOROGENIC PROBES FOR MEDIUM CHAIN ACYL-COA DEHYDROGENASE ( MCAD ) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2007-02-22 | — | — | WO | disclosed |