SCHEMBL5594041

SCHEMBL5594041

CON1C(C)(C)c2cccc3cccc(c23)C1(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.38
HPGD P15428 5/20 0.38
KDM4E B2RXH2 5/20 0.38
MAPT P10636 4/20 0.38
GAA P10253 4/20 0.38
HSD17B10 Q99714 3/20 0.38
NSD2 O96028 2/20 0.38
APP P05067 1/20 0.38
SNCA P37840 1/20 0.38
RAD52 P43351 1/20 0.35
TYMS P04818 1/20 0.34
KMT2A Q03164 3/20 0.33
CYP1A2 P05177 2/20 0.33
MEN1 O00255 2/20 0.33
MAPK1 P28482 1/20 0.33
CYP1A1 P04798 1/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
CYP1B1 Q16678 1/20 0.33
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9157168 0.81 SMN1; SMN2 (0.33) ALDH1A1KDM4EMAPTGAAKMT2A
SCHEMBL14392561 0.75 ALDH1A1 (0.41) ALDH1A1HPGDKDM4EMAPTGAA
SCHEMBL5594716 0.70 RAD52 (0.45) ALDH1A1HPGDKDM4EMAPTGAA
SCHEMBL23351420 0.68 ALDH1A1 (0.62) ALDH1A1HPGDKDM4EMAPTGAA
SCHEMBL14262737 0.67 RAD52 (0.41) ALDH1A1HPGDKDM4EMAPTGAA
SCHEMBL5604278 0.67 NPSR1 (0.42) ALDH1A1HPGDKDM4EMAPTGAA
SCHEMBL11959150 0.67 ALDH1A1 (0.42) ALDH1A1HPGDKDM4EMAPTGAA
SCHEMBL21662875 0.64 KDM4E (0.39) ALDH1A1HPGDKDM4EMAPTGAA
SCHEMBL31395712 0.64 ALDH1A1 (0.50) ALDH1A1HPGDKDM4EMAPTGAA
SCHEMBL13447549 0.63 ALDH1A1 (0.33) ALDH1A1KDM4EMAPTGAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007124543-A1 PROFLUORESCENT NITROXIDE COMPOUNDS QUEENSLAND UNIVERSITY OF TECHNOLOGY (AU) 2007-11-08 WO disclosed
WO-2007124543-A1 PROFLUORESCENT NITROXIDE COMPOUNDS QUEENSLAND UNIVERSITY OF TECHNOLOGY (AU) 2007-11-08 WO disclosed