Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | GAA | P10253 | 2/20 | 0.71 |
| ▸ | RAB9A | P51151 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | UBE2N | P61088 | 3/20 | 0.68 |
| ▸ | ATM | Q13315 | 2/20 | 0.68 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.66 |
| ▸ | CA1 | P00915 | 1/20 | 0.66 |
| ▸ | CA2 | P00918 | 1/20 | 0.66 |
| ▸ | CA9 | Q16790 | 1/20 | 0.66 |
| ▸ | CLTC | Q00610 | 1/20 | 0.64 |
| ▸ | CASP3 | P42574 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | RECQL | P46063 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720966 | 0.88 | NPSR1 (0.79) | NPSR1KDM4EMAPTALDH1A1GAA | |
| SCHEMBL27169540 | 0.85 | NPSR1 (0.73) | NPSR1KDM4EMAPTALDH1A1GAA | |
| SCHEMBL12431370 | 0.85 | NPSR1 (0.73) | NPSR1MAPTALDH1A1CYP1B1CA12 | |
| SCHEMBL28277900 | 0.85 | NPSR1 (0.73) | NPSR1KDM4EMAPTALDH1A1GAA | |
| SCHEMBL28737144 | 0.85 | UBE2N (0.81) | NPSR1KDM4EMAPTALDH1A1GAA | |
| SCHEMBL30472950 | 0.85 | CASP3 (0.85) | NPSR1KDM4EMAPTALDH1A1CYP1B1 | |
| SCHEMBL326305 | 0.85 | CASP3 (0.85) | NPSR1KDM4EMAPTALDH1A1CYP1B1 | |
| SCHEMBL8153395 | 0.84 | NPSR1 (0.72) | NPSR1KDM4EMAPTALDH1A1GAA | |
| SCHEMBL28284669 | 0.83 | ALDH1A1 (1.00) | NPSR1KDM4EMAPTALDH1A1GAA | |
| SCHEMBL28737148 | 0.82 | UBE2N (0.82) | NPSR1KDM4EMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112143253-B | Cationic fluorescent dye based on benzyl naphthalimide structure and preparation and application thereof | 盐城东吴化工有限公司 | 2022-07-05 | — | — | CN | claimed |
| CN-112143253-A | Cationic fluorescent dye based on benzyl naphthalimide structure and preparation and application thereof | 盐城东吴化工有限公司 | 2020-12-29 | — | — | CN | claimed |
| CN-113717104-B | Preparation and application of leveling cationic fluorescent dye containing long carbon chain | 盐城东吴化工有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-113831286-B | Gemini type naphthalimide cationic fluorescent dye and preparation method thereof | 东华大学 | 2023-02-28 | — | — | CN | disclosed |
| CN-112143253-B | Cationic fluorescent dye based on benzyl naphthalimide structure and preparation and application thereof | 盐城东吴化工有限公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-112143253-B | Cationic fluorescent dye based on benzyl naphthalimide structure and preparation and application thereof | 盐城东吴化工有限公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-112143253-B | Cationic fluorescent dye based on benzyl naphthalimide structure and preparation and application thereof | 盐城东吴化工有限公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-109928927-B | Application of two-photon fluorescent probe for detecting cytochrome oxidase CYP3A4 | 大连医科大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-113831286-A | Gemini naphthalimide cationic fluorescent dye and preparation method thereof | 东华大学 | 2021-12-24 | — | — | CN | disclosed |
| CN-113717104-A | Preparation and application of leveling cationic fluorescent dye containing long carbon chain | 盐城东吴化工有限公司 | 2021-11-30 | — | — | CN | disclosed |
| CN-112143253-A | Cationic fluorescent dye based on benzyl naphthalimide structure and preparation and application thereof | 盐城东吴化工有限公司 | 2020-12-29 | — | — | CN | disclosed |
| CN-112143253-A | Cationic fluorescent dye based on benzyl naphthalimide structure and preparation and application thereof | 盐城东吴化工有限公司 | 2020-12-29 | — | — | CN | disclosed |
| CN-112143253-A | Cationic fluorescent dye based on benzyl naphthalimide structure and preparation and application thereof | 盐城东吴化工有限公司 | 2020-12-29 | — | — | CN | disclosed |
| CN-110272388-A | 4- dithiocarbonic acid piperazine -3- nitro -1,8- naphthalimide derivative and its synthetic method and application | 桂林医学院 | 2019-09-24 | — | — | CN | disclosed |
| CN-109928927-A | Application of two-photon type fluorescent probe for detecting cytochrome oxidase CYP3A4 | 大连医科大学 | 2019-06-25 | — | — | CN | disclosed |
| WO-2007124543-A1 | PROFLUORESCENT NITROXIDE COMPOUNDS | QUEENSLAND UNIVERSITY OF TECHNOLOGY (AU) | 2007-11-08 | — | — | WO | disclosed |
| WO-2007124543-A1 | PROFLUORESCENT NITROXIDE COMPOUNDS | QUEENSLAND UNIVERSITY OF TECHNOLOGY (AU) | 2007-11-08 | — | — | WO | disclosed |