Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.56 |
| ▸ | CFTR | P13569 | 1/20 | 0.52 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole SCHEMBL9783935 | 0.86 | ALDH1A1 (0.50) | SLC6A2SLC6A4SLC6A3ALDH1A1FKBP5 | |
| Imidazole SCHEMBL9783956 | 0.83 | ALDH1A1 (0.46) | SLC6A2SLC6A4SLC6A3ALDH1A1FKBP5 | |
| Biphenyl SCHEMBL27756385 | 0.82 | ALDH1A1 (0.62) | SLC6A2SLC6A4SLC6A3ALDH1A1FKBP5 | |
| Biphenyl SCHEMBL986473 | 0.82 | ALDH1A1 (0.62) | SLC6A2SLC6A4SLC6A3ALDH1A1FKBP5 | |
| Benzene SCHEMBL5088215 | 0.81 | ALDH1A1 (0.87) | ALDH1A1FKBP5 | |
| Benzene SCHEMBL18279961 | 0.81 | ALDH1A1 (0.87) | ALDH1A1FKBP5 | |
| Benzene SCHEMBL29168770 | 0.81 | ALDH1A1 (0.87) | ALDH1A1FKBP5 | |
| Biphenyl SCHEMBL28667880 | 0.80 | ALDH1A1 (0.59) | ALDH1A1FKBP5KMT2AATMCYP19A1 | |
| Biphenyl SCHEMBL28151555 | 0.80 | ALDH1A1 (0.59) | ALDH1A1FKBP5KMT2AATMCYP19A1 | |
| Naphthalene SCHEMBL2123892 | 0.79 | ALDH1A1 (0.65) | SLC6A2SLC6A4SLC6A3ALDH1A1FKBP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1158971-B1 | GARDOS CHANNEL ANTAGONISTS | ICAGEN INC (US) | 2007-08-22 | — | — | EP | disclosed |