Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole SCHEMBL9783346 | 0.83 | HRH1 (0.44) | ALDH1A1FKBP5SLC6A2SLC6A4SLC6A3 | |
| Imidazole SCHEMBL5594401 | 0.83 | SLC6A2 (0.58) | ALDH1A1FKBP5SLC6A2SLC6A4SLC6A3 | |
| Imidazole SCHEMBL9783935 | 0.81 | ALDH1A1 (0.50) | ALDH1A1FKBP5SLC6A2SLC6A4SLC6A3 | |
| Imidazole SCHEMBL9783016 | 0.80 | CYP19A1 (0.44) | ALDH1A1FKBP5SLC6A2CYP19A1 | |
| Imidazole SCHEMBL9783730 | 0.79 | ALDH1A1 (0.36) | ALDH1A1FKBP5SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8852211 | 0.76 | HTR2A (0.52) | HTR2ATAAR1HRH1 | |
| Imidazole SCHEMBL9676326 | 0.75 | ALDH1A1 (0.56) | ALDH1A1FKBP5SLC6A2SLC6A4SLC6A3 | |
| Biphenyl SCHEMBL986473 | 0.74 | ALDH1A1 (0.62) | ALDH1A1FKBP5SLC6A2SLC6A4SLC6A3 | |
| Biphenyl SCHEMBL27756385 | 0.74 | ALDH1A1 (0.62) | ALDH1A1FKBP5SLC6A2SLC6A4SLC6A3 | |
| Benzene SCHEMBL18279961 | 0.73 | ALDH1A1 (0.87) | ALDH1A1FKBP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051514-A | Complexing boranes and imidazoles | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0432987-A2 | Fungicidal organoborane imidazole compounds and intermediates therefor | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4983589-A | Fungicidal imidazole diphenylaliphaticboranes and derivatives thereof | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-01-08 | — | — | US | disclosed |