Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 5/20 | 0.49 |
| ▸ | BLM | P54132 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | S100A4 | P26447 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 8/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | APEX1 | P27695 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5595450 | 0.85 | KMT2A (0.56) | KMT2APOLBBLMGAANSD2 | |
| SCHEMBL5595188 | 0.82 | EGFR (0.62) | KMT2APOLBBLMGAANSD2 | |
| SCHEMBL10476360 | 0.77 | MEN1 (0.60) | KMT2APOLBBLMGAAMEN1 | |
| SCHEMBL5594539 | 0.77 | MIF (0.55) | KMT2APOLBBLMGAANSD2 | |
| SCHEMBL5594770 | 0.76 | MEN1 (0.59) | KMT2APOLBBLMS100A4MEN1 | |
| SCHEMBL5594374 | 0.73 | S100A4 (0.46) | KMT2APOLBBLMGAANSD2 | |
| SCHEMBL5604921 | 0.72 | CYP1A2 (0.47) | KMT2AS100A4LMNAKDM4ETDP1 | |
| SCHEMBL5604915 | 0.72 | CYP1A2 (0.47) | KMT2AS100A4LMNAKDM4ETDP1 | |
| SCHEMBL3248262 | 0.66 | EGFR (0.82) | KMT2APOLBBLMGAAMEN1 | |
| SCHEMBL2599092 | 0.65 | S100A4 (1.00) | KMT2APOLBBLMGAANSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778176-B1 | COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO KGAA (DE) | 2012-07-25 | — | — | EP | disclosed |
| EP-1778176-A2 | MEANS FOR COLOURING KERATIN-CONTAINING FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-05-02 | — | — | EP | disclosed |
| WO-2005120445-A2 | MEANS FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-12-22 | — | — | WO | disclosed |