Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.56 |
| ▸ | MEN1 | O00255 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | BLM | P54132 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | RGS12 | O14924 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10476360 | 0.87 | MEN1 (0.60) | KMT2AMEN1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL5594864 | 0.85 | KMT2A (0.49) | KMT2AMEN1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL5604915 | 0.81 | CYP1A2 (0.47) | KMT2AKDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5604921 | 0.81 | CYP1A2 (0.47) | KMT2AKDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5595188 | 0.78 | EGFR (0.62) | KMT2AMEN1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL8749247 | 0.76 | DNM1 (0.61) | KMT2AMEN1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL5164387 | 0.76 | DNM1 (0.61) | KMT2AMEN1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL5594977 | 0.74 | KMT2A (0.57) | KMT2AMEN1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL23530140 | 0.74 | ALDH1A1 (0.75) | KMT2AMEN1MAPTDNM1ALDH1A1 | |
| SCHEMBL2211505 | 0.74 | ALDH1A1 (0.75) | KMT2AMEN1MAPTDNM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778176-B1 | COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO KGAA (DE) | 2012-07-25 | — | — | EP | disclosed |
| EP-1778176-A2 | MEANS FOR COLOURING KERATIN-CONTAINING FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-05-02 | — | — | EP | disclosed |
| WO-2005120445-A2 | MEANS FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-12-22 | — | — | WO | disclosed |