SCHEMBL5595170

SCHEMBL5595170

CCCc1ccc(-c2cccc(-c3ccccc3)c2)cc1

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.53
KCNH2 Q12809 1/20 0.52
TAAR1 Q96RJ0 3/20 0.50
FFAR1 O14842 1/20 0.47
MAOB P27338 4/20 0.46
HSD11B1 P28845 2/20 0.46
KDM4E B2RXH2 1/20 0.46
NPC1 O15118 1/20 0.46
ALDH1A1 P00352 1/20 0.46
MAPT P10636 1/20 0.46
PKM P14618 1/20 0.46
HPGD P15428 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HSD17B10 Q99714 1/20 0.46
SIGMAR1 Q99720 1/20 0.44
BCL2 P10415 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1951510 0.91 FFAR1 (0.54) MCL1KCNH2TAAR1FFAR1HSD11B1
SCHEMBL10078136 0.88 AGXT (0.50) MCL1KDM4ENPC1ALDH1A1MAPT
SCHEMBL15238584 0.88 MCL1 (0.49) MCL1KCNH2TAAR1FFAR1MAOB
Ethyne SCHEMBL28568325 0.87 FFAR1 (0.50) MCL1KCNH2TAAR1FFAR1HSD11B1
SCHEMBL4533749 0.85 AGXT (0.52) KDM4ENPC1ALDH1A1MAPTPKM
SCHEMBL22053558 0.84 MCL1 (0.48) MCL1KCNH2TAAR1FFAR1MAOB
SCHEMBL19843583 0.84 BCL2 (0.57) MCL1KCNH2TAAR1MAOBNPC1
SCHEMBL28842020 0.83 FFAR1 (0.52) MCL1KCNH2TAAR1FFAR1HSD11B1
Boric Acid SCHEMBL31374401 0.83 LPL (0.55) MCL1KCNH2TAAR1FFAR1HSD11B1
Bicarbonate SCHEMBL27643185 0.83 FFAR1 (0.62) MCL1FFAR1ALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7181156-B2 Image forming apparatus using a cleaning member for preventing noises and process cartridge therefor RICOH COMPANY, LTD. (JP) 2007-02-20 US disclosed
US-20050069357-A1 Image forming apparatus and process cartridge therefor RICOH COMPANY, LTD (JP) 2005-03-31 US disclosed
US-5561016-A HAVING PHOTOCONDUCTIVE LAYER CONTAINING CHARGE GENERATING MATERIAL, POLYVINYL BUTYRAL BINDER, CHARGE TRANSPORTING MATERIAL AND BIPHENYL(OR DERIVATIVE) ON ELECTROCONDUCTIVE SUPPORT RICOH COMPANY, LTD. (JP) 1996-10-01 US disclosed