SCHEMBL5596018

SCHEMBL5596018

OCC(O)C(O)C(O)c1cnc(C(O)C(O)C(O)CO)cn1

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.43
LMNA P02545 2/20 0.43
TDP1 Q9NUW8 1/20 0.42
KDM4E B2RXH2 2/20 0.32
PDE4A P27815 1/20 0.32
CYP1A2 P05177 1/20 0.31
APLNR P35414 2/20 0.31
USP2 O75604 1/20 0.30
SLCO1B1 Q9Y6L6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6741377 1.00 L3MBTL1 (0.43) L3MBTL1LMNATDP1KDM4EPDE4A
SCHEMBL6744312 1.00 L3MBTL1 (0.43) L3MBTL1LMNATDP1KDM4EPDE4A
SCHEMBL29386641 1.00 L3MBTL1 (0.43) L3MBTL1LMNATDP1KDM4EPDE4A
SCHEMBL6743153 1.00 L3MBTL1 (0.43) L3MBTL1LMNATDP1KDM4EPDE4A
SCHEMBL6741431 1.00 L3MBTL1 (0.43) L3MBTL1LMNATDP1KDM4EPDE4A
SCHEMBL6743645 1.00 L3MBTL1 (0.43) L3MBTL1LMNATDP1KDM4EPDE4A
SCHEMBL6740419 1.00 L3MBTL1 (0.43) L3MBTL1LMNATDP1KDM4EPDE4A
SCHEMBL6740171 1.00 L3MBTL1 (0.43) L3MBTL1LMNATDP1KDM4EPDE4A
SCHEMBL28291225 0.89 LMNA (0.34) L3MBTL1LMNATDP1KDM4E
SCHEMBL8342848 0.86 LMNA (0.35) L3MBTL1LMNATDP1APLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040209890-A1 Polyhydroxyalkylpyrazine derivatives, their preparation and medicaments comprising them BASHIARDES GEORGES 2004-10-21 US claimed
EP-0998465-B1 POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM AVENTIS PHARMA SA (FR) 2003-09-10 EP claimed
US-6392042-B1 ANTIDIABETIC AGENTS AVENTIS PHARMA S.A. (FR) 2002-05-21 US claimed
WO-2024158254-A1 METHOD FOR PRODUCING N-BOC-SPHINGOSINE AND SPHINGOSINE-1-PHOSPHATE (주)유케이케미팜 2024-08-02 WO disclosed
CN-114901086-B Tobacco treatment 英美烟草(投资)有限公司 2024-05-31 CN disclosed
US-20220400734-A1 TOBACCO TREATMENT BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED (GB) 2022-12-22 US disclosed
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
CN-114901086-A Tobacco treatment 英美烟草(投资)有限公司 2022-08-12 CN disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed
EP-1675938-B1 BEVERAGES AND FOODSTUFFS RESISTANT TO LIGHT INDUCED FLAVOUR CHANGES, PROCESSES FOR MAKING THE SAME, AND COMPOSITIONS FOR IMPARTING SUCH RESISTANCE HEINEKEN SUPPLY CHAIN BV (NL) 2007-06-06 EP disclosed
US-20070116817-A1 Beverages and foodstuffs resistant to light induced flavor changes, processes for making the same, and compositions for imparting such resistance HEINEKEN SUPPLY CHAIN B.V. (NL) 2007-05-24 US disclosed
US-20070071850-A1 Beverages and foodstuffs resistant to light induced flavour changes, processes for making the same, and compositions for imparting such resistance VAN DER ARK RICHARD 2007-03-29 US disclosed
WO-2005030920-A9 BEVERAGES AND FOODSTUFFS RESISTANT TO LIGHT INDUCED FLAVOUR CHANGES, PROCESSES FOR MAKING THE SAME, AND COMPOSITIONS FOR IMPARTING SUCH RESISTANCE HEINEKEN SUPPLY CHAIN BV (NL) 2006-12-07 WO disclosed
EP-1675938-A1 BEVERAGES AND FOODSTUFFS RESISTANT TO LIGHT INDUCED FLAVOUR CHANGES, PROCESSES FOR MAKING THE SAME, AND COMPOSITIONS FOR IMPARTING SUCH RESISTANCE Heineken Supply Chain B.V. (NL) 2006-07-05 EP disclosed
WO-2005030920-A1 BEVERAGES AND FOODSTUFFS RESISTANT TO LIGHT INDUCED FLAVOUR CHANGES, PROCESSES FOR MAKING THE SAME, AND COMPOSITIONS FOR IMPARTING SUCH RESISTANCE HEINEKEN SUPPLY CHAIN B.V. (NL) 2005-04-07 WO disclosed
US-20040209890-A1 Polyhydroxyalkylpyrazine derivatives, their preparation and medicaments comprising them BASHIARDES GEORGES 2004-10-21 US disclosed
EP-0998465-B1 POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM AVENTIS PHARMA SA (FR) 2003-09-10 EP disclosed
US-6392042-B1 ANTIDIABETIC AGENTS AVENTIS PHARMA S.A. (FR) 2002-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040209890-A1 Polyhydroxyalkylpyrazine derivatives, their preparation and medicaments comprising them SLC5A2, HK2, HRH2 L3MBTL1 4794/4885LMNA 4447/4885TDP1 4417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.