SCHEMBL5596035

SCHEMBL5596035

OC/C=P(=C\CO)/Cc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.44
TDP1 Q9NUW8 2/20 0.41
MAOB P27338 1/20 0.37
CALM1 P0DP23 1/20 0.36
CYP1A2 P05177 1/20 0.35
IDO1 P14902 2/20 0.34
THRB P10828 1/20 0.34
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
AKR1B1 P15121 1/20 0.34
HPGD P15428 1/20 0.34
TRPA1 O75762 2/20 0.33
LMNA P02545 2/20 0.33
HIF1A Q16665 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
TP53 P04637 1/20 0.33
SLC22A2 O15244 1/20 0.33
SLC22A1 O15245 1/20 0.33
ADRA2A P08913 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5596316 0.70 TSHR (0.41) TSHRTDP1MAOBCALM1IDO1
SCHEMBL5596320 0.70 TSHR (0.41) TSHRTDP1MAOBCALM1IDO1
SCHEMBL5596289 0.69 TSHR (0.50) TSHRTDP1MAOBCALM1IDO1
SCHEMBL1304376 0.67 TSHR (0.48) TSHRTDP1MAOBCALM1IDO1
SCHEMBL2129272 0.67 TSHR (0.48) TSHRTDP1MAOBCALM1IDO1
SCHEMBL5595992 0.67 TDP1 (0.39) TSHRTDP1LMNATP53ALDH1A1
Benzyl Alcohol SCHEMBL10317948 0.66
SCHEMBL196203 0.66 CALM1 (0.50) TSHRTDP1MAOBCALM1IDO1
SCHEMBL5595993 0.65 TDP1 (0.48) TSHRTDP1MAOBCALM1IDO1
SCHEMBL18408878 0.64 CALM1 (0.47) TSHRTDP1MAOBCALM1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7279537-B2 Transition metal complexes and polymerization catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-10-09 US disclosed
US-20060229195-A1 Transition metal complexes and polymerization catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-10-12 US disclosed
EP-1557423-A1 TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS Sumitomo Chemical Company, Limited (JP) 2005-07-27 EP disclosed