Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596115 | 0.82 | CA2 (0.48) | CA2GABRA1GABRB2ALOX12ALDH1A1 | |
| SCHEMBL5596958 | 0.82 | CA2 (0.48) | CA2GABRA1GABRB2ALOX12ALDH1A1 | |
| SCHEMBL20942945 | 0.81 | CA2 (0.61) | CA2GABRA1GABRB2ALOX12ALDH1A1 | |
| SCHEMBL5596229 | 0.79 | CA2 (0.64) | CA2GABRA1GABRB2ALOX12ALDH1A1 | |
| SCHEMBL5596347 | 0.77 | CA2 (0.61) | CA2GABRA1GABRB2ALOX12ALDH1A1 | |
| SCHEMBL38598 | 0.75 | CA2 (1.00) | CA2GABRA1GABRB2ALOX12ALDH1A1 | |
| SCHEMBL5596935 | 0.75 | ALDH1A1 (0.52) | CA2GABRA1GABRB2ALDH1A1TSHR | |
| SCHEMBL5596969 | 0.74 | CA2 (0.57) | CA2GABRA1GABRB2ALOX12ALDH1A1 | |
| SCHEMBL5596921 | 0.74 | CA2 (0.57) | CA2GABRA1GABRB2ALOX12ALDH1A1 | |
| SCHEMBL6275546 | 0.73 | CA2 (0.55) | CA2GABRA1GABRB2ALOX12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |