SCHEMBL5596108

SCHEMBL5596108

Cc1cc(P(c2ccccc2)c2cc(C)cc(C(C)(C)C)c2O)c(O)c(C(C)(C)C)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
ALDH1A1 P00352 2/20 0.53
POLB P06746 1/20 0.53
TYR P14679 1/20 0.53
HSPA5 P11021 1/20 0.45
CYP2C9 P11712 4/20 0.44
CYP2C19 P33261 4/20 0.44
HIF1A Q16665 2/20 0.44
TSHR P16473 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
CYP2D6 P10635 1/20 0.40
HSD17B10 Q99714 1/20 0.40
PTGS2 P35354 2/20 0.38
PTGS1 P23219 1/20 0.38
CA1 P00915 1/20 0.37
MEN1 O00255 1/20 0.37
GAA P10253 1/20 0.37
KMT2A Q03164 1/20 0.37
CYP1A2 P05177 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28661482 0.82 ESR1 (0.41) CA2SMN1; SMN2ALDH1A1POLBTYR
SCHEMBL8006016 0.82 CA2 (0.47) CA2SMN1; SMN2ALDH1A1POLBTYR
SCHEMBL7193235 0.81 TSHR (0.49) CA2SMN1; SMN2ALDH1A1POLBTYR
SCHEMBL5596086 0.78 CA2 (0.55) CA2ALDH1A1CYP2C9CYP2C19TSHR
SCHEMBL24503616 0.78 ALDH1A1 (0.46) CA2SMN1; SMN2ALDH1A1POLBTYR
SCHEMBL12774794 0.78 HSPA5 (0.46) CA2SMN1; SMN2ALDH1A1POLBTYR
SCHEMBL10567591 0.78 CA2 (0.48) CA2SMN1; SMN2ALDH1A1POLBTYR
SCHEMBL10567856 0.78 CA2 (0.48) CA2SMN1; SMN2ALDH1A1POLBTYR
Butylated Hydroxytoluene SCHEMBL3134340 0.77 CA2 (0.75) CA2SMN1; SMN2ALDH1A1POLBTYR
SCHEMBL12774746 0.77 ALDH1A1 (0.45) CA2SMN1; SMN2ALDH1A1POLBTYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9104691-A None JP disclosed
US-7279537-B2 Transition metal complexes and polymerization catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-10-09 US disclosed
US-20060229195-A1 Transition metal complexes and polymerization catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-10-12 US disclosed
EP-1557423-A1 TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS Sumitomo Chemical Company, Limited (JP) 2005-07-27 EP disclosed
JP-H09104691-A PHOSPHORUS ATOM-CROSS-LINKED BISPHENOL DERIVATIVE AND ITS PRODUCTION SUMITOMO CHEM CO LTD 1997-04-22 JP disclosed