SCHEMBL5596158

SCHEMBL5596158

C[Si](C)(C)c1cccc(P(c2cccc([Si](C)(C)C)c2O)[Si](C)(C)c2ccccc2)c1O

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5596626 0.87 ESR1 (0.35) ESR1ESR2
SCHEMBL5596527 0.81 ALDH1A1 (0.43) ESR1ESR2
SCHEMBL5596858 0.80 IDO1 (0.32)
SCHEMBL5596115 0.78 CA2 (0.48) ESR1ESR2
SCHEMBL5596914 0.77 ESR1 (0.41) ESR1ESR2
SCHEMBL5596177 0.76 ESR1 (0.39) ESR1ESR2
SCHEMBL5596281 0.74 IDO1 (0.36)
SCHEMBL5595937 0.72 PTPN22 (0.43)
SCHEMBL5596003 0.72 KCNH2 (0.31)
SCHEMBL3119798 0.71 ALDH1A1 (0.41) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7279537-B2 Transition metal complexes and polymerization catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-10-09 US disclosed
US-20060229195-A1 Transition metal complexes and polymerization catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-10-12 US disclosed
EP-1557423-A1 TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS Sumitomo Chemical Company, Limited (JP) 2005-07-27 EP disclosed