SCHEMBL5596227

SCHEMBL5596227

CCP(c1cc(C)cc(C)c1O)c1cc(C)cc(C)c1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
KDM4E B2RXH2 2/20 0.43
GAA P10253 2/20 0.43
MAPT P10636 2/20 0.43
LMNA P02545 1/20 0.43
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
CA2 P00918 2/20 0.36
SELL P14151 1/20 0.36
SELP P16109 1/20 0.36
SELE P16581 1/20 0.36
CA1 P00915 1/20 0.36
NR3C1 P04150 1/20 0.33
PGR P06401 1/20 0.33
NR3C2 P08235 1/20 0.33
PTGS1 P23219 3/20 0.32
PTGS2 P35354 3/20 0.32
TP53 P04637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5597004 0.84 ALDH1A1 (0.41) ALDH1A1KDM4EGAAMAPTLMNA
SCHEMBL5596042 0.81 ALDH1A1 (0.38) ALDH1A1KDM4EGAAMAPTLMNA
SCHEMBL5596384 0.78 HTT (0.49) ALDH1A1GAAESR1PTGS1PTGS2
SCHEMBL5596273 0.77 CYP3A4 (0.41) ALDH1A1ESR1ESR2CA2CA1
SCHEMBL5596197 0.76 ALDH1A1 (0.48) ALDH1A1KDM4EGAAMAPTLMNA
SCHEMBL5596553 0.74 TYR (0.39) ALDH1A1KDM4EMAPTPTGS2TP53
SCHEMBL5596432 0.74 GAA (0.40) ALDH1A1KDM4EGAAMAPTLMNA
SCHEMBL5596863 0.72 ALDH1A1 (0.45) ALDH1A1KDM4EGAAMAPTLMNA
SCHEMBL27800318 0.71 ALDH1A1 (0.65) ALDH1A1KDM4EGAAMAPTLMNA
SCHEMBL36529 0.71 ALDH1A1 (0.65) ALDH1A1KDM4EGAAMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7279537-B2 Transition metal complexes and polymerization catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-10-09 US disclosed
US-20060229195-A1 Transition metal complexes and polymerization catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-10-12 US disclosed
EP-1557423-A1 TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS Sumitomo Chemical Company, Limited (JP) 2005-07-27 EP disclosed