Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | SELL | P14151 | 1/20 | 0.33 |
| ▸ | SELP | P16109 | 1/20 | 0.33 |
| ▸ | SELE | P16581 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596042 | 0.89 | ALDH1A1 (0.38) | ALDH1A1KDM4ELMNAGAAMAPT | |
| SCHEMBL5596227 | 0.84 | ALDH1A1 (0.43) | ALDH1A1KDM4ELMNAGAAMAPT | |
| SCHEMBL5596496 | 0.81 | HTT (0.47) | ALDH1A1GAAHPGDPTGS1PTGS2 | |
| SCHEMBL5595988 | 0.79 | CYP3A4 (0.40) | ALDH1A1ESR1ESR2CA1CA2 | |
| SCHEMBL5596404 | 0.78 | HTT (0.38) | ALDH1A1KDM4ELMNAMAPTHPGD | |
| SCHEMBL5596489 | 0.74 | HTT (0.47) | ALDH1A1GAAHPGDPTGS1PTGS2 | |
| SCHEMBL5595971 | 0.73 | ALDH1A1 (0.48) | ALDH1A1KDM4ELMNAGAAMAPT | |
| SCHEMBL5596924 | 0.73 | ALOX15 (0.45) | ALDH1A1LMNAGAAMAPTESR1 | |
| SCHEMBL5596197 | 0.73 | ALDH1A1 (0.48) | ALDH1A1KDM4ELMNAGAAMAPT | |
| SCHEMBL17529758 | 0.72 | TDP1 (0.37) | ALDH1A1TP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |