Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5595937 | 0.87 | PTPN22 (0.43) | PTPN22LDHACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL5596903 | 0.83 | PTPN22 (0.53) | PTPN22LDHACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5596121 | 0.77 | PTPN22 (0.43) | PTPN22CYP1A2CYP2C9HPGDCYP2C19 | |
| SCHEMBL5596608 | 0.73 | ALDH1A1 (0.43) | CYP2C9HPGDHSD17B10KMT2A | |
| SCHEMBL5596424 | 0.73 | PTPN22 (0.54) | PTPN22LDHACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL5596626 | 0.72 | ESR1 (0.35) | — | |
| SCHEMBL5596474 | 0.72 | ESR1 (0.41) | HPGDHIF1AHSD17B10NPC1RAB9A | |
| SCHEMBL5596299 | 0.70 | PTPN22 (0.50) | PTPN22LDHACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL5596306 | 0.70 | PTPN22 (0.50) | PTPN22LDHACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL5596958 | 0.70 | CA2 (0.48) | CYP1A2CYP2C9CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |