Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RCE1 | Q9Y256 | 4/20 | 0.43 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596131 | 0.77 | PTPN22 (0.43) | RCE1PTPN22CYP1A2CYP2C9HPGD | |
| SCHEMBL5596615 | 0.72 | ALDH1A1 (0.42) | CYP1A2CYP2C9HPGDCYP2C19HSD17B10 | |
| SCHEMBL5596479 | 0.72 | ALDH1A1 (0.35) | CYP2D6HPGDHIF1AHSD17B10 | |
| SCHEMBL5596306 | 0.70 | PTPN22 (0.50) | PTPN22LDHACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL5596299 | 0.70 | PTPN22 (0.50) | PTPN22LDHACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL5596424 | 0.70 | PTPN22 (0.54) | PTPN22LDHACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL5596633 | 0.69 | — | — | |
| SCHEMBL5596960 | 0.69 | CA2 (0.47) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9749915 | 0.67 | RCE1 (0.61) | RCE1PTPN22LDHAHSP90AA1CYP1A2 | |
| SCHEMBL28091317 | 0.67 | PTPN22 (0.73) | RCE1PTPN22LDHACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |