Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 4/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fenyripol SCHEMBL828783 | 0.82 | CYP2D6 (0.70) | CYP2D6KDM4EL3MBTL1AOC3NPC1 | |
| Fenyripol SCHEMBL120829 | 0.81 | CYP2D6 (0.68) | CYP2D6KDM4EL3MBTL1AOC3NPC1 | |
| SCHEMBL5759858 | 0.76 | IDH2 (0.35) | KDM4E | |
| SCHEMBL5832242 | 0.73 | ESR1 (0.43) | SMN1; SMN2 | |
| SCHEMBL5597057 | 0.71 | HPGD (0.54) | KDM4EL3MBTL1SMN1; SMN2HPGDMAPK1 | |
| SCHEMBL2638609 | 0.71 | HDAC3 (0.48) | HPGD | |
| Phenyramidol SCHEMBL13310227 | 0.70 | CYP2D6 (1.00) | CYP2D6KDM4EL3MBTL1AOC3HTT | |
| Phenyramidol SCHEMBL13310219 | 0.70 | CYP2D6 (1.00) | CYP2D6KDM4EL3MBTL1AOC3HTT | |
| Phenyramidol SCHEMBL29500950 | 0.70 | CYP2D6 (1.00) | CYP2D6KDM4EL3MBTL1AOC3HTT | |
| Phenyramidol SCHEMBL21963 | 0.70 | CYP2D6 (1.00) | CYP2D6KDM4EL3MBTL1AOC3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696909-B1 | BENZOTHIAZOLE DERIVATIVES FOR THE TREATMENT OF DIABETES | SERONO LAB (CH) | 2007-11-14 | — | — | EP | claimed |