Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SCD | O00767 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | BAP1 | Q92560 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12153235 | 0.76 | USP2 (0.58) | USP2ALDH1A1SCDMEN1KMT2A | |
| SCHEMBL5633033 | 0.75 | USP2 (0.58) | USP2ALDH1A1SCDMEN1KMT2A | |
| SCHEMBL2884104 | 0.74 | ALDH1A1 (0.42) | USP2ALDH1A1SCDMEN1KMT2A | |
| Lithium Ion SCHEMBL5633232 | 0.73 | USP2 (0.57) | USP2ALDH1A1SCDMEN1KMT2A | |
| SCHEMBL5596653 | 0.73 | SCD (0.42) | USP2ALDH1A1SCDMEN1KMT2A | |
| SCHEMBL11201625 | 0.73 | USP2 (0.58) | USP2ALDH1A1SCDMEN1KMT2A | |
| SCHEMBL13875589 | 0.72 | USP2 (0.63) | USP2ALDH1A1SCDMEN1KMT2A | |
| SCHEMBL8253693 | 0.72 | USP2 (0.59) | USP2ALDH1A1SCDMEN1KMT2A | |
| SCHEMBL16372562 | 0.71 | USP2 (0.66) | USP2ALDH1A1SCDMEN1KMT2A | |
| SCHEMBL29152989 | 0.71 | USP2 (0.66) | USP2ALDH1A1SCDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696909-B1 | BENZOTHIAZOLE DERIVATIVES FOR THE TREATMENT OF DIABETES | SERONO LAB (CH) | 2007-11-14 | — | — | EP | claimed |
| EP-1240164-B1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | APPLIED RESEARCH SYSTEMS (AN) | 2003-11-12 | — | — | EP | claimed |
| EP-1240164-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001047920-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-07-05 | — | — | WO | disclosed |
| EP-1110957-A1 | Benzazole derivatives and their use as JNK modulators | Applied Research Systems ARS Holding N.V. (AN) | 2001-06-27 | — | — | EP | disclosed |