Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL7559335 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TSHRFFAR3LCKFYN | |
| Ether SCHEMBL7763625 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TSHRFFAR3LCKFYN | |
| Ether SCHEMBL115545 | 0.97 | — | — | |
| Ether SCHEMBL20338904 | 0.97 | ALDH1A1 (0.50) | ALDH1A1TSHRFFAR3LCKFYN | |
| Ether SCHEMBL7115101 | 0.97 | ALDH1A1 (0.50) | ALDH1A1TSHRFFAR3LCKFYN | |
| Ether SCHEMBL28393262 | 0.97 | ALDH1A1 (0.50) | ALDH1A1TSHRFFAR3LCKFYN | |
| Ether SCHEMBL28328411 | 0.97 | ALDH1A1 (0.50) | ALDH1A1TSHRFFAR3LCKFYN | |
| Ether SCHEMBL11311472 | 0.93 | ALDH1A1 (0.48) | ALDH1A1TSHRFFAR3LCKFYN | |
| Ether SCHEMBL6524630 | 0.93 | ALDH1A1 (0.48) | ALDH1A1TSHRFFAR3LCKFYN | |
| Ether SCHEMBL9317524 | 0.93 | ALDH1A1 (0.48) | ALDH1A1TSHRFFAR3LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115430525-B | Adjustable ester group-containing quaternary ammonium salt flotation collector for magnesite flotation desilication, preparation method, compound collector and application thereof | 淄博坤鑫选矿药剂有限公司 | 2024-01-26 | — | — | CN | claimed |
| CN-117085836-A | Gravity separation-reverse flotation cold crystallization method for treating potassium mixed salt ore | 中蓝连海设计研究院有限公司 | 2023-11-21 | — | — | CN | claimed |
| CN-115430525-A | Flotation collecting agent containing adjustable ester-based quaternary ammonium salt and capable of being used for flotation desilication of magnesite, preparation method, compound collecting agent and application thereof | 淄博坤鑫选矿药剂有限公司 | 2022-12-06 | — | — | CN | claimed |
| CN-108940563-B | Carbon silicon collophanite cation reverse flotation desilication method based on foam regulation | 中蓝长化工程科技有限公司 | 2020-11-06 | — | — | CN | claimed |
| CN-104971821-A | Method for treating potassium mixed salt through dense media and obverse floatation process | CHINA BLUESTAR LEHIGH ENG CORP | 2015-10-14 | — | — | CN | claimed |
| CN-104858066-A | Direct-reverse flotation process for preparing high-purity sulfur concentrate | CHINA BLUESTAR LEHIGH ENG CORP | 2015-08-26 | — | — | CN | claimed |
| CN-104826741-A | Flotation and backwater method aiming at collophanite double-back flotation process | CHINA BLUESTAR LEHIGH ENG CORP | 2015-08-12 | — | — | CN | claimed |
| CN-104815750-A | Pre-concentration method for solid sylvinite ore | CHINA BLUESTAR LEHIGH ENG CORP | 2015-08-05 | — | — | CN | claimed |
| CN-104624387-A | Floatation and purification method for quartz stone pulverized through heating power | UNIV NORTHEASTERN | 2015-05-20 | — | — | CN | claimed |
| CN-115430525-B | Adjustable ester group-containing quaternary ammonium salt flotation collector for magnesite flotation desilication, preparation method, compound collector and application thereof | 淄博坤鑫选矿药剂有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-117085836-A | Gravity separation-reverse flotation cold crystallization method for treating potassium mixed salt ore | 中蓝连海设计研究院有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-113857209-B | Red mud recycling method and application thereof | 南华大学 | 2023-01-24 | — | — | CN | disclosed |
| CN-115430525-A | Flotation collecting agent containing adjustable ester-based quaternary ammonium salt and capable of being used for flotation desilication of magnesite, preparation method, compound collecting agent and application thereof | 淄博坤鑫选矿药剂有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-113857209-A | Red mud recycling method and application thereof | 南华大学 | 2021-12-31 | — | — | CN | disclosed |
| US-5693133-A | COMPRISING ASPHALT CUTBACK (ASPHALT AND SOLVENT) AND A SALT OF A FATTY AMINE AND INORGANIC OR ORGANIC ACID AS DISPERSANT; MATERIALS HANDLING; STORAGE STABILITY; HIGH VISCOSITY; THIXOTROPIC | AKZO NOBEL NV (NL) | 1997-12-02 | — | — | US | disclosed |
| US-5047120-A | Method for manufacture of lightweight frothed mineral wool panel | USG INTERIORS, INC. (US) | 1991-09-10 | — | — | US | disclosed |
| EP-0297132-A4 | METHOD FOR MANUFACTURE OF LIGHTWEIGHT FROTHED MINERAL WOOL PANEL | — | 1991-08-28 | — | — | EP | disclosed |
| EP-0297132-A1 | METHOD FOR MANUFACTURE OF LIGHTWEIGHT FROTHED MINERAL WOOL PANEL | USG INTERIORS, Inc. (US) | 1989-01-04 | — | — | EP | disclosed |
| WO-1988005100-A1 | METHOD FOR MANUFACTURE OF LIGHTWEIGHT FROTHED MINERAL WOOL PANEL | USG INTERIORS, INC. (US) | 1988-07-14 | — | — | WO | disclosed |
| US-4422928-A | AMINOPROPYL ETHERS | EXXON RESEARCH & ENGINEERING CO. (US) | 1983-12-27 | — | — | US | disclosed |