Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.35 |
| ▸ | LSS | P48449 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4269757 | 0.93 | ALDH1A1 (0.46) | ALDH1A1TSHRKDM4ESMN1; SMN2DNM1 | |
| SCHEMBL530011 | 0.87 | ALDH1A1 (0.53) | ALDH1A1TSHRKDM4ESMN1; SMN2HRH3 | |
| SCHEMBL2106534 | 0.84 | — | — | |
| SCHEMBL9651294 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM4ESMN1; SMN2HRH3 | |
| SCHEMBL623374 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM4ESMN1; SMN2HRH3 | |
| SCHEMBL10566857 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM4ESMN1; SMN2HRH3 | |
| SCHEMBL4274493 | 0.82 | — | — | |
| SCHEMBL22813038 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TSHRKDM4ESMN1; SMN2HRH3 | |
| Water SCHEMBL9578060 | 0.81 | ALDH1A1 (0.47) | ALDH1A1TSHRKDM4ESMN1; SMN2HRH3 | |
| SCHEMBL476584 | 0.81 | ALDH1A1 (0.47) | ALDH1A1TSHRKDM4ESMN1; SMN2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647675-A | Rhodamine dyes | BASF AKTIENGESELLSCHAFT (DE) | 1987-03-03 | — | — | US | claimed |
| EP-1829876-A1 | NITROGENEOUS TRICYCLIC COMPOUND | Asahi Kasei Pharma Corporation (JP) | 2007-09-05 | — | — | EP | disclosed |
| US-20060247266-A1 | Nitrogen-containing tricyclic compounds | ASAHI KASEI PHARMA CORPORATION (JP) | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247266-A1 | Nitrogen-containing tricyclic compounds | MYO1B, CHRM1, MYL12A | ALDH1A1 3199/4885TSHR 699/4885KDM4E 3043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.