Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL11244098 | 1.00 | CES2 (0.44) | CES2DNM1TSHRNAAATP53 | |
| Acetic Acid SCHEMBL11239123 | 1.00 | CES2 (0.44) | CES2DNM1TSHRNAAATP53 | |
| SCHEMBL116257 | 0.88 | DNM1 (0.54) | DNM1TSHR | |
| SCHEMBL446396 | 0.88 | DNM1 (0.54) | DNM1TSHR | |
| SCHEMBL10822148 | 0.88 | DNM1 (0.54) | DNM1TSHR | |
| SCHEMBL3029039 | 0.88 | DNM1 (0.54) | DNM1TSHR | |
| SCHEMBL496059 | 0.88 | DNM1 (0.54) | DNM1TSHR | |
| SCHEMBL379293 | 0.88 | DNM1 (0.54) | DNM1TSHR | |
| SCHEMBL8752601 | 0.88 | DNM1 (0.54) | DNM1TSHR | |
| SCHEMBL116910 | 0.88 | DNM1 (0.54) | DNM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4759799-A | Clay and alkyloxypropylamine salt surfactant | EXXON CHEMICAL PATENTS INC. (US) | 1988-07-26 | — | — | US | claimed |
| US-20070169668-A1 | ASPHALT-BASED COATING COMPOSITIONS AND SALT SURFACTANTS | TOMAH PRODUCTS, INC. | 2007-07-26 | — | — | US | disclosed |
| EP-1811004-A1 | Asphalt-based coating compositions and salt surfactants | Tomah Products, Inc. (US) | 2007-07-25 | — | — | EP | disclosed |
| US-7238230-B1 | Asphalt-based coating compositions and salt surfactants | TOMAH PRODUCTS, INC. (US) | 2007-07-03 | — | — | US | disclosed |
| US-5730791-A | ROOF COATING INCLUDING CLAY | TOMAH PRODUCTS, INC. (US) | 1998-03-24 | — | — | US | disclosed |
| US-5622554-A | HIGH VISCOSITY; NONFLAMMABLE; ODORLESS | TOMAH PRODUCTS, INC. (US) | 1997-04-22 | — | — | US | disclosed |
| US-5618340-A | ROOFING | TOMAH PRODUCTS, INC. (US) | 1997-04-08 | — | — | US | disclosed |
| US-4759799-A | Clay and alkyloxypropylamine salt surfactant | EXXON CHEMICAL PATENTS INC. (US) | 1988-07-26 | — | — | US | disclosed |
| US-4319987-A | Branched alkyl ether amines as iron ore flotation aids | EXXON RESEARCH & ENGINEERING CO. (US) | 1982-03-16 | — | — | US | disclosed |