Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | CASP9 | P55211 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.31 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7376583 | 0.85 | CYP1A2 (0.37) | CYP1A2CYP2A6MAOACES1 | |
| SCHEMBL9847703 | 0.70 | CYP1A2 (0.42) | CYP1A2CYP2A6MAOACES1BCHE | |
| SCHEMBL16720889 | 0.69 | MEN1 (0.43) | CYP1A2CYP2A6MAOA | |
| SCHEMBL29366435 | 0.69 | CYP1A2 (1.00) | CYP1A2CYP2A6MAOACES1BCHE | |
| SCHEMBL77106 | 0.69 | CYP1A2 (1.00) | CYP1A2CYP2A6MAOACES1BCHE | |
| SCHEMBL195129 | 0.68 | CYP1A2 (0.31) | CYP1A2 | |
| SCHEMBL3649668 | 0.67 | MAOB (0.38) | CYP1A2CYP2A6MAOACES1BCHE | |
| SCHEMBL10845533 | 0.67 | CYP2A6 (0.48) | CYP1A2CYP2A6MAOACES1BCHE | |
| SCHEMBL10463768 | 0.66 | CYP1A2 (0.94) | CYP1A2CYP2A6MAOACES1BCHE | |
| Ammonia Solution, Strong SCHEMBL13736473 | 0.66 | CYP1A2 (0.94) | CYP1A2CYP2A6MAOACES1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112358479-B | Synthesis method of pyrrolo [3,4-c ] quinoline-1, 3-dione compound | 西北师范大学 | 2023-06-16 | — | — | CN | claimed |
| CN-105705147-B | Novel oxazolidone antimicrobial compound | 李药业有限公司 | 2019-06-28 | — | — | CN | claimed |
| EP-0660824-A1 | 1,2 DIHYDRO-3-H-DIBENZ(de,h) ISOQUINOLINE 1,3 DIONE AND THEIR USE AS ANTICANCER AGENTS | RESEARCH CORPORATION TECHNOLOGIES (US) | 1995-07-05 | — | — | EP | claimed |
| CN-113214220-B | Substituted 4-aminoisoindoline-1, 3-dione compounds and their use for the treatment of lymphomas | 细胞基因公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-112358479-B | Synthesis method of pyrrolo [3,4-c ] quinoline-1, 3-dione compound | 西北师范大学 | 2023-06-16 | — | — | CN | disclosed |
| CN-113784969-A | PLK1 Selective degradation inducing Compounds | 厄普特拉公司 | 2021-12-10 | — | — | CN | disclosed |
| CN-113164775-A | Polycyclic compounds and methods for rapid accelerated targeted degradation of fibrosarcoma polypeptides | 阿尔维纳斯运营股份有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-112358479-A | Synthesis method of pyrrolo [3,4-c ] quinoline-1, 3-diketone compound | 西北师范大学 | 2021-02-12 | — | — | CN | disclosed |
| US-10251392-B2 | Antimicrobial devices and compositions | AVENT, INC. (US) | 2019-04-09 | — | — | US | disclosed |
| US-9289378-B2 | Antimicrobial amorphous compositions | AVENT, INC. (US) | 2016-03-22 | — | — | US | disclosed |
| EP-2789235-B1 | Method of preparing silver nanoparticles | AVENT INC (US) | 2015-12-23 | — | — | EP | disclosed |
| EP-1507778-A4 | ANTI-TUMOUR POLYCYCLIC CARBOXAMIDES | UNIV TROBE (AU) | 2006-05-31 | — | — | EP | disclosed |
| EP-1507778-A1 | ANTI-TUMOUR POLYCYCLIC CARBOXAMIDES | LA TROBE UNIVERSITY (AU) | 2005-02-23 | — | — | EP | disclosed |
| WO-2003097642-A1 | ANTI-TUMOUR POLYCYCLIC CARBOXAMIDES | LA TROBE UNIVERSITY (AU) | 2003-11-27 | — | — | WO | disclosed |
| EP-1144381-A2 | SUBSTITUTED BENZO[DE]ISOQUINOLINE-1,3-DIONES | MERCK PATENT GmbH (DE) | 2001-10-17 | — | — | EP | disclosed |
| EP-1133475-A1 | SUBSTITUTED BENZO DE]ISOQUINOLINE-1,3-DIONES | MERCK PATENT GmbH (DE) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000032577-A2 | SUBSTITUTED BENZO[DE]ISOQUINOLINE-1,3-DIONES | MERCK PATENT GMBH (DE) | 2000-06-08 | — | — | WO | disclosed |
| WO-2000031039-A1 | SUBSTITUTED BENZO[DE]ISOQUINOLINE-1,3-DIONES | MERCK PATENT GMBH (DE) | 2000-06-02 | — | — | WO | disclosed |
| EP-0480939-A1 | HETEROCYCLIC AMINES HAVING CENTRAL NERVOUS SYSTEM ACTIVITY. | UPJOHN CO (US) | 1992-04-22 | — | — | EP | disclosed |
| EP-0296048-A1 | Derivatives of piperazinyl alkyl piperazine dione, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1988-12-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10251392-B2 | Antimicrobial devices and compositions | AAAS, AOC1, COL14A1 | CYP1A2 3226/4885CYP2A6 1650/4885MAOA 2338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.