SCHEMBL9847703

SCHEMBL9847703

O=C1Cc2ccccc2[N+]1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.42
MAOA P21397 2/20 0.38
CYP2A6 P11509 1/20 0.37
CES1 P23141 2/20 0.35
BCHE P06276 1/20 0.35
AHR P35869 1/20 0.34
PDK2 Q15119 1/20 0.34
ANPEP P15144 4/20 0.32
TDP2 O95551 1/20 0.32
CASP3 P42574 1/20 0.32
CASP7 P55210 1/20 0.32
CASP9 P55211 1/20 0.32
CASP6 P55212 1/20 0.32
CASP8 Q14790 1/20 0.32
MAP3K14 Q99558 1/20 0.32
MAOB P27338 1/20 0.31
ALDH1A1 P00352 3/20 0.31
HPGD P15428 2/20 0.31
RNASEH1 O60930 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5597402 0.70 CYP1A2 (0.50) CYP1A2MAOACYP2A6CES1BCHE
SCHEMBL5697095 0.68 CYP1A2 (0.32) CYP1A2
SCHEMBL7337539 0.66 CYP1A2 (0.35) CYP1A2MAOACYP2A6CES1BCHE
SCHEMBL4756605 0.64 BRPF1 (0.38) CYP1A2AHRPDK2KDM4ECA12
SCHEMBL10677670 0.64 HTR6 (0.32) CYP1A2
SCHEMBL8577962 0.64 MAOA (0.38) CYP1A2MAOACYP2A6CES1BCHE
SCHEMBL11304912 0.64 MAOB (0.39) CYP1A2MAOACYP2A6MAOBALDH1A1
SCHEMBL15516801 0.62 CYP1A2 (0.52) CYP1A2MAOACYP2A6CES1BCHE
SCHEMBL77106 0.61 CYP1A2 (1.00) CYP1A2MAOACYP2A6CES1BCHE
SCHEMBL31392781 0.61 CYP1A2 (0.67) CYP1A2MAOACYP2A6CES1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434844-A1 NEW CYCLIC ANTHRANILIC ACID DERIVATIVE AND METHOD OF PRODUCING THE SAME KYORIN PHARMACEUTICAL CO., LTD. (JP) 1991-07-03 EP disclosed