Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.33 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6791005 | 0.85 | ALDH1A1 (0.38) | ALDH1A1KDM4CMAPTGAAMAPK10 | |
| SCHEMBL7528234 | 0.81 | ALDH1A1 (0.38) | ALDH1A1KDM4CMAPTGAAMAPK10 | |
| SCHEMBL10620249 | 0.81 | ALDH1A1 (0.41) | ALDH1A1KDM4CMAPTGAAMAPK10 | |
| SCHEMBL5308318 | 0.78 | ALDH1A1 (0.44) | ALDH1A1KDM4CMAPTGAA | |
| SCHEMBL11827573 | 0.78 | ALDH1A1 (0.38) | ALDH1A1KDM4CMAPTGAAMAPK10 | |
| SCHEMBL11380557 | 0.77 | PTGER3 (0.38) | PTGER3 | |
| SCHEMBL6798684 | 0.76 | HSD17B2 (0.40) | ALDH1A1KDM4CGAA | |
| SCHEMBL6798968 | 0.76 | HSD17B2 (0.40) | ALDH1A1KDM4CGAA | |
| SCHEMBL6786610 | 0.76 | HSD17B2 (0.40) | ALDH1A1KDM4CGAA | |
| SCHEMBL2163156 | 0.76 | ALDH1A1 (0.53) | ALDH1A1KDM4CMAPTGAADAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007191446-A | BIPHENYLMETHYLHYDANTOIN COMPOUND, METHOD FOR PRODUCING THE SAME AND METHOD FOR PRODUCING BIPHENYLALANINE COMPOUND USING THE SAME | SUMITOMO CHEMICAL CO LTD | 2007-08-02 | — | — | JP | disclosed |
| US-5530016-A | HYPOTENSIVE AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |