Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6798968 | 0.90 | HSD17B2 (0.40) | ALDH1A1KDM4CGAAEPHX1HSD17B2 | |
| SCHEMBL6798684 | 0.90 | HSD17B2 (0.40) | ALDH1A1KDM4CGAAEPHX1HSD17B2 | |
| SCHEMBL6786610 | 0.90 | HSD17B2 (0.40) | ALDH1A1KDM4CGAAEPHX1HSD17B2 | |
| SCHEMBL6792155 | 0.86 | SRD5A2 (0.43) | LMNA | |
| SCHEMBL6703699 | 0.83 | BACE1 (0.32) | — | |
| SCHEMBL6794517 | 0.83 | PTGS1 (0.46) | ALDH1A1GAALMNAHSD17B2 | |
| SCHEMBL5597472 | 0.81 | ALDH1A1 (0.40) | ALDH1A1KDM4CGAAMAPTUSP2 | |
| SCHEMBL6702888 | 0.81 | HSD17B2 (0.41) | ALDH1A1MAPTHSD17B2 | |
| SCHEMBL6841040 | 0.81 | MEN1 (0.35) | ALDH1A1KDM4CGAAEPHX1MAPT | |
| SCHEMBL6791191 | 0.80 | MMP2 (0.35) | ALDH1A1GAAMAPTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63079879-A | — | — | None | — | — | JP | disclosed |
| JP-S6379879-A | PRODUCTION OF HYDANTOINS | MITSUI TOATSU CHEM INC | 1988-04-09 | — | — | JP | disclosed |