Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ6 | P48051 | 10/20 | 0.41 |
| ▸ | KCNJ3 | P48549 | 10/20 | 0.41 |
| ▸ | KCNJ5 | P48544 | 7/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DDX3X | O00571 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5597907 | 0.84 | DDX3X (0.57) | KCNJ6KCNJ3KCNJ5DDX3XMEN1 | |
| SCHEMBL5597514 | 0.84 | TRPV1 (0.44) | KCNJ6KCNJ3KCNJ5DDX3XMEN1 | |
| SCHEMBL5597942 | 0.84 | TP53 (0.47) | KCNJ6KCNJ3KCNJ5MEN1ALDH1A1 | |
| SCHEMBL5597878 | 0.82 | MEN1 (0.53) | POLBMEN1ALDH1A1MAPTHTT | |
| SCHEMBL5597764 | 0.82 | NPC1 (0.53) | KCNJ6KCNJ3KCNJ5MEN1LMNA | |
| SCHEMBL5597503 | 0.82 | AAK1 (0.45) | KCNJ6KCNJ3KCNJ5POLBMEN1 | |
| SCHEMBL7050959 | 0.81 | HDAC6 (0.44) | KCNJ6KCNJ3KCNJ5MEN1KMT2A | |
| SCHEMBL5597510 | 0.81 | KCNJ6 (0.41) | KCNJ6KCNJ3KCNJ5POLBDDX3X | |
| SCHEMBL5597880 | 0.81 | RXFP1 (0.44) | KCNJ6KCNJ3KCNJ5MEN1ALDH1A1 | |
| SCHEMBL5597681 | 0.81 | TP53 (0.54) | MEN1ALDH1A1LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202734-B1 | 3(5)-UREIDO-PYRAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR AGENTS | PFIZER ITALIA SRL (IT) | 2007-05-02 | — | — | EP | claimed |
| US-6387900-B1 | ANTICANCER AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2002-05-14 | — | — | US | claimed |
| EP-1202734-B1 | 3(5)-UREIDO-PYRAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR AGENTS | PFIZER ITALIA SRL (IT) | 2007-05-02 | — | — | EP | disclosed |
| US-6387900-B1 | ANTICANCER AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2002-05-14 | — | — | US | disclosed |