SCHEMBL5597693

SCHEMBL5597693

NS(=O)(=O)c1ncc2nccc-2[nH]1

nearest known ligand 0.32

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA13 Q8N1Q1 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
IKBKB O14920 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4058006 0.74 CA2 (0.43) CA12CA1CA2CA4CA5A
Hydrogen Sulfide SCHEMBL28246976 0.70
SCHEMBL985896 0.68 GSK3B (0.46) CYP4F2CYP4A11IKBKB
Sulfamide SCHEMBL27407275 0.68 ASIC3 (0.38) CYP4F2CYP4A11
SCHEMBL28393579 0.67 MAPT (0.36)
SCHEMBL127415 0.67 MAPT (0.36)
SCHEMBL128068 0.67 CDK5 (0.32)
SCHEMBL3858640 0.67 CYP2A6 (0.47)
SCHEMBL3644139 0.67 NPY5R (0.31)
SCHEMBL129499 0.67 NPY5R (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0565593-B1 REDUCING PESTICIDAL INTERACTIONS IN CROPS MONSANTO CO (US) 1999-03-03 EP claimed
EP-0603240-B1 SAFENING HERBICIDAL PYRAZOLYLSULFONYLUREAS MONSANTO CO (US) 1998-12-02 EP claimed
US-5484760-A AMIDES MONSANTO COMPANY (US) 1996-01-16 US claimed
EP-0603240-A1 SAFENING HERBICIDAL PYRAZOLYLSULFONYLURES MONSANTO COMPANY (US) 1994-06-29 EP claimed
EP-0565593-A1 REDUCING PESTICIDAL INTERACTIONS IN CROPS MONSANTO COMPANY (US) 1993-10-20 EP claimed
EP-0531271-A1 Safening herbicidal pyrazolysulfonylureas MONSANTO COMPANY (US) 1993-03-10 EP claimed
WO-1993003615-A1 SAFENING HERBICIDAL PYRAZOLYLSULFONYLURES MONSANTO COMPANY (US) 1993-03-04 WO claimed
WO-1992011761-A1 REDUCING PESTICIDAL INTERACTIONS IN CROPS MONSANTO COMPANY (US) 1992-07-23 WO claimed
EP-1338199-B1 Herbicidal compositions BASF AG (DE) 2007-05-30 EP disclosed
CN-1066313-C Safened herbicidal sulfonamide compositions MONSANTO CO (US) 2001-05-30 CN disclosed
CN-1066313-C Safened herbicidal sulfonamide compositions MONSANTO CO (US) 2001-05-30 CN disclosed
US-5880066-A COMPOSITION COMPRISING TRIAZOLOPYRIMIDINE SULFONAMIDE HERBICIDE AND OXAZOLIDINE DICHLOROACETAMIDE ANTIDOTE MONSANTO COMPANY (US) 1999-03-09 US disclosed
US-5880066-A COMPOSITION COMPRISING TRIAZOLOPYRIMIDINE SULFONAMIDE HERBICIDE AND OXAZOLIDINE DICHLOROACETAMIDE ANTIDOTE MONSANTO COMPANY (US) 1999-03-09 US disclosed
EP-0565593-B1 REDUCING PESTICIDAL INTERACTIONS IN CROPS MONSANTO CO (US) 1999-03-03 EP disclosed
CN-1063015-A Safe herbicidal sulfonamide compositions MONSANTO CO (US) 1992-07-29 CN disclosed
CN-1063015-A Safe herbicidal sulfonamide compositions MONSANTO CO (US) 1992-07-29 CN disclosed
WO-1992011761-A1 REDUCING PESTICIDAL INTERACTIONS IN CROPS MONSANTO COMPANY (US) 1992-07-23 WO disclosed
WO-1992010098-A1 SAFENED HERBICIDAL SULFONAMIDE COMPOSITIONS MONSANTO COMPANY (US) 1992-06-25 WO disclosed
EP-0332029-A2 Triazolopyrimidine-2-sulfon amides BAYER AG (DE) 1989-09-13 EP disclosed
EP-0268951-A2 Triazolopyrimidine-2-sulphone amides BAYER AG (DE) 1988-06-01 EP disclosed