SCHEMBL5597758

SCHEMBL5597758

C=C(C)C(=O)OC.C=C[Si](OCC)(OCC)OCC

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.54
THRB P10828 1/20 0.38
TSHR P16473 3/20 0.36
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL11793510 0.85 ALDH1A1 (0.39) ALDH1A1TSHR
Methacrylic Acid SCHEMBL7915019 0.83 THRB (0.33) ALDH1A1THRB
Acetone SCHEMBL9580410 0.82 ALDH1A1 (0.35) ALDH1A1TSHR
SCHEMBL27875083 0.81 ALDH1A1 (0.62) ALDH1A1THRBTSHR
Acetic Acid SCHEMBL27814033 0.81 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL28269629 0.80 THRB (0.49) ALDH1A1THRBTSHR
Butanone SCHEMBL28827453 0.79 ALDH1A1 (0.43) ALDH1A1TSHR
SCHEMBL27858743 0.78 ALDH1A1 (0.58) ALDH1A1TSHR
SCHEMBL6216027 0.77 TSHR (0.44) THRBTSHR
Propane SCHEMBL23527365 0.76 ALDH1A1 (0.83) ALDH1A1THRBTSHRMGAMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1312639-A1 Rubber composition comprised of functionalized elastomer and starch composite with coupling agent and tire having at least one component thereof THE GOODYEAR TIRE & RUBBER COMPANY (US) 2003-05-21 EP claimed
US-20030092801-A1 Rubber composition comprised of functionalized elastomer and starch composite with coupling agent and tire having at least one component thereof RIDDELL, INC. 2003-05-15 US claimed
CN-107352856-B A kind of airfield pavement patching material and preparation method thereof 山东建筑大学 2019-11-26 CN disclosed
EP-1312639-B1 Rubber composition comprised of functionalized elastomer and starch composite with coupling agent and tire having at least one component thereof GOODYEAR TIRE & RUBBER (US) 2007-05-30 EP disclosed
EP-1457520-B1 Process of preparing a silica-rich rubber composition for a tire by a series of sequential mixing steps GOODYEAR TIRE & RUBBER (US) 2006-12-20 EP disclosed
US-7122586-B2 Preparation of silica-rich rubber composition by sequential mixing with maximum mixing temperature limitations THE GOODYEAR TIRE & RUBBER COMPANY (US) 2006-10-17 US disclosed
US-20040181004-A1 Preparation of silica-rich rubber composition by sequential mixing with maximum mixing temperature limitations THE GOODYEAR TIRE & RUBBER COMPANY 2004-09-16 US disclosed
EP-1457520-A1 Process of preparing a silica-rich rubber composition for a tire by a series of sequential mixing steps THE GOODYEAR TIRE & RUBBER COMPANY (US) 2004-09-15 EP disclosed
EP-1312639-A1 Rubber composition comprised of functionalized elastomer and starch composite with coupling agent and tire having at least one component thereof THE GOODYEAR TIRE & RUBBER COMPANY (US) 2003-05-21 EP disclosed
US-20030092801-A1 Rubber composition comprised of functionalized elastomer and starch composite with coupling agent and tire having at least one component thereof RIDDELL, INC. 2003-05-15 US disclosed