Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | DRD4 | P21917 | 3/20 | 0.46 |
| ▸ | DRD3 | P35462 | 3/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | NAPEPLD | Q6IQ20 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5597755 | 0.88 | DRD2 (0.42) | DRD2DRD4DRD3HCAR3CDC7 | |
| SCHEMBL27565140 | 0.84 | MBTPS1 (0.40) | DRD2DRD4DRD3NAPEPLDEPHX2 | |
| SCHEMBL27584810 | 0.80 | KMT2A (0.35) | KMT2A | |
| Chlorobenzene SCHEMBL27565141 | 0.75 | DRD2 (0.37) | DRD2DRD4DRD3CDC7KMT2A | |
| SCHEMBL27584820 | 0.74 | KMT2A (0.42) | DRD2DRD4DRD3SMYD3EPHX2 | |
| SCHEMBL27584981 | 0.74 | HCAR2 (0.43) | CDC7 | |
| SCHEMBL27565003 | 0.73 | CDC7 (0.37) | CDC7 | |
| SCHEMBL28747748 | 0.72 | CNR1 (0.37) | DRD2DRD4DRD3CDC7MEN1 | |
| SCHEMBL27565130 | 0.72 | CDC7 (0.36) | CDC7ALDH1A1 | |
| SCHEMBL27584804 | 0.72 | SYK (0.37) | DRD2DRD4DRD3CDC7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202734-B1 | 3(5)-UREIDO-PYRAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR AGENTS | PFIZER ITALIA SRL (IT) | 2007-05-02 | — | — | EP | disclosed |