Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | DRD4 | P21917 | 3/20 | 0.42 |
| ▸ | DRD3 | P35462 | 3/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CPB1 | P15086 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5597777 | 0.88 | DRD2 (0.46) | DRD2DRD4DRD3CDC7HCAR3 | |
| SCHEMBL27565003 | 0.84 | CDC7 (0.37) | CDC7S1PR3S1PR1CCNA2CDK2 | |
| SCHEMBL28747748 | 0.83 | CNR1 (0.37) | DRD2DRD4DRD3CDC7SMN1; SMN2 | |
| SCHEMBL27565130 | 0.83 | CDC7 (0.36) | CDC7LMNAALDH1A1CCNA2CDK2 | |
| SCHEMBL27584981 | 0.83 | HCAR2 (0.43) | CDC7CCNA2CDK2CCNA1 | |
| SCHEMBL27584980 | 0.80 | CCNA2 (0.47) | CCNA2CDK2CCNA1KMT2AMEN1 | |
| SCHEMBL27584807 | 0.80 | MGLL (0.43) | SMN1; SMN2KDM4ECCNA2CDK2CCNA1 | |
| SCHEMBL27584810 | 0.77 | KMT2A (0.35) | KMT2A | |
| Chlorobenzene SCHEMBL27565141 | 0.77 | DRD2 (0.37) | DRD2DRD4DRD3CDC7KDM4E | |
| SCHEMBL27584802 | 0.77 | ALOX5 (0.45) | LMNASMN1; SMN2ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202734-B1 | 3(5)-UREIDO-PYRAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR AGENTS | PFIZER ITALIA SRL (IT) | 2007-05-02 | — | — | EP | disclosed |