Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5597636 | 0.88 | ALDH1A1 (0.47) | HIF1AHTTALDH1A1KDM4ETSHR | |
| SCHEMBL5598036 | 0.86 | HIF1A (0.46) | HIF1AALDH1A1TSHRLMNATDP1 | |
| SCHEMBL5597762 | 0.84 | TSHR (0.48) | HIF1AALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL3625149 | 0.83 | HIF1A (0.47) | HIF1AALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL8203671 | 0.83 | HIF1A (0.47) | HIF1AALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL3625146 | 0.83 | HIF1A (0.47) | HIF1AALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL5597923 | 0.83 | TSHR (0.49) | HIF1AALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL5597784 | 0.82 | HIF1A (0.46) | HIF1AALDH1A1TSHRLMNAGAA | |
| SCHEMBL5597921 | 0.82 | HIF1A (0.42) | HIF1AHTTALDH1A1TSHR | |
| SCHEMBL5597674 | 0.82 | HTT (0.43) | HTTCYP19A1ALDH1A1KDM4EPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765304-B2 | METHOD OF PREPARING ALPHA-METHOXYIMINOCARBOXYLIC ACID METHYLAMIDES, AND INTERMEDIATES USED IN THE METHOD | BAYER CROPSCIENCE AG (DE) | 2007-08-22 | — | — | EP | claimed |