Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5597961 | 0.78 | NTRK1 (0.42) | NISCHNTRK1 | |
| SCHEMBL5610548 | 0.74 | PDPK1 (0.34) | NISCHNTRK1 | |
| SCHEMBL25478238 | 0.71 | NISCH (0.35) | NISCH | |
| SCHEMBL755641 | 0.65 | IMPDH2 (0.39) | NISCH | |
| SCHEMBL15848550 | 0.62 | ALDH1A1 (0.41) | — | |
| SCHEMBL27690947 | 0.59 | NISCH (0.58) | NISCH | |
| SCHEMBL24782866 | 0.58 | NISCH (0.55) | NISCHNTRK1 | |
| SCHEMBL7698513 | 0.56 | NISCH (0.52) | NISCH | |
| SCHEMBL28175769 | 0.56 | GSK3B (0.36) | — | |
| SCHEMBL27767101 | 0.56 | NISCH (0.52) | NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539763-A4 | AZAINDOLE KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2007-08-01 | — | — | EP | disclosed |
| EP-1539763-A1 | AZAINDOLE KINASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004009601-A1 | AZAINDOLE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-01-29 | — | — | WO | disclosed |