Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | GID4 | Q8IVV7 | 4/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18977551 | 0.82 | PRCP (0.47) | PRCPGAAGID4RECQLKDM1A | |
| SCHEMBL11679676 | 0.80 | PRCP (0.45) | PRCPGAAGID4KDM1ADRD2 | |
| Hydrochloric Acid SCHEMBL11852646 | 0.79 | PRCP (0.44) | PRCPGAAGID4KDM1ADRD2 | |
| SCHEMBL11854994 | 0.76 | PRCP (0.40) | PRCPGAAGID4RECQLKDM1A | |
| SCHEMBL11681688 | 0.76 | KIF11 (0.44) | PRCPGAAKDM1AMEN1KMT2A | |
| SCHEMBL28404587 | 0.74 | GAA (0.33) | PRCPGAARECQLKDM1AMEN1 | |
| SCHEMBL11679672 | 0.74 | USP7 (0.48) | PRCPKDM1AMEN1KMT2AMAPT | |
| SCHEMBL30423150 | 0.73 | PDGFRA (0.41) | PRCPMEN1KMT2ALMNAMAPT | |
| SCHEMBL1045807 | 0.73 | PDGFRA (0.41) | PRCPMEN1KMT2ALMNAMAPT | |
| SCHEMBL18977121 | 0.73 | PRCP (0.39) | PRCPGAAGID4RECQLKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007072041-A1 | THERAPEUTIC COMPOUNDS | ASTEX THERAPEUTICS LIMITED (GB) | 2007-06-28 | — | — | WO | disclosed |