Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PRCP | P42785 | 2/20 | 0.32 |
| ▸ | F12 | P00748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6076273 | 0.82 | ALDH1A1 (0.33) | GAAMEN1KMT2AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL4630224 | 0.80 | TSHR (0.32) | GAAALDH1A1TSHRNPSR1 | |
| SCHEMBL5598091 | 0.74 | PRCP (0.55) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6979173 | 0.74 | TSHR (0.57) | GAAALDH1A1MAPTTSHRNPSR1 | |
| SCHEMBL224810 | 0.73 | F12 (0.36) | GAAMEN1KMT2AALDH1A1KDM1A | |
| SCHEMBL2172225 | 0.73 | F12 (0.36) | GAAMEN1KMT2AALDH1A1KDM1A | |
| SCHEMBL2172550 | 0.73 | F12 (0.36) | GAAMEN1KMT2AALDH1A1KDM1A | |
| SCHEMBL30290030 | 0.73 | F12 (0.36) | GAAMEN1KMT2AALDH1A1KDM1A | |
| Hydrochloric Acid SCHEMBL27979283 | 0.72 | ALDH1A1 (0.37) | GAAMEN1KMT2AALDH1A1KDM1A | |
| SCHEMBL27766970 | 0.72 | GPR3 (0.34) | GAAMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111278840-A | Pyrrolo [2, 3-B ] pyridine compounds and their use for treating cancer | 癌症研究科技有限公司 | 2020-06-12 | — | — | CN | disclosed |
| CN-110997068-A | Radiolabeled fluorescent PARP inhibitors for imaging and radiotherapy | 宾夕法尼亚大学董事会 | 2020-04-10 | — | — | CN | disclosed |